Society of Diabetic Nephropathy Prevention Annals of Research in Antioxidants 2476-5511 3 1 2018 01 03 Administration of herbal antioxidant to prevent and treatment of cancers e02 e02 EN Banafsheh Yalameha REVIEW 2017 11 05 2018 01 01 Cancer is known as the second leading cause of death in industrialized countries. Nowadays, the use of plants in prevention and treatment of diseases such as cancer to be increased. Plants contain different compounds such as herbal antioxidants that play a vital role with anti-proliferative and cytotoxic properties through biochemical and molecular mechanisms in different cancers like liver, breast, lung, prostate, leukemia, colon and ovarian cancers. Antioxidant compounds found in different herbal medicines and fruits that used in prevention or treatment of cancers. Considering the findings, it can be concluded that herbal antioxidants have a significant and useful effect on types of cancer cells via regulation expression of many genes involve in cancers.