Abstract
Kidneys are the potential organs that play the important roles in controlling concentrations of body fluid, acid-base balance as well as blood and urine volume. Chronic renal failure especially hemodialysis causes the high mortality risk in patients. One of the causes of hemodialysis and mortality is the generation of reactive oxygen species (ROS). Thus, to control and to mitigate the adverse effects of dialysis in these patients, dietary antioxidants including vitamin C and flavonoids are necessary. Therefore, the aim of this review article is to clarify the effects of antioxidant therapy on hemodialysis patients.